Conoidin A

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Purity: ≥98%

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2,3-Bis(bromomethyl)quinoxaline 1,4-dioxide

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Appearance:Crystalline Solid
Application:For research use only.
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Peroxiredoxins are a ubiquitous family of antioxidant enzymes that also control cytokine-induced peroxide levels and thereby mediate signal transduction in mammalian cells. Conoidin A inactivates peroxiredoxins by covalently binding to the catalytic cysteine on the enzyme. It has been shown to inhibit peroxiredoxin II (IC50 = 23 μM) in the parasite T. gondii and peroxiredoxin I in the hookworm A. ceylanicum.

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