DL-threo-PDMP hydrochloride

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Purity: ≥98%

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DL-PDMP D,l-Threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol HCl

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Appearance:Crystalline Solid
Application:For research use only.
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DL-threo PDMP is a mixture of ceramide analogs that contains two of the four possible stereoisomers of PDMP: D-threo (1R,2R) and L-threo (1S,2S) PDMP. DL-threo-PDMP inhibits glucosylceramide synthase by 33 and 48% in MDCK cell homogenates when used at concentrations of 5 and 10 μM. It reduces the synthesis of glucosylceramide, increases cellular ceramide, and induces cell cycle arrest in vitro.

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