IDN-6556 IDN6556
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Emricasan is a pan-caspase inhibitor with antiapoptotic and antiinflammatory activity. It was shown that emricasan decreased caspase activity, serum alanine aminotransferase (ALT), and hepatic fibrogenesis in a murine model of non-alcoholic steatohepatitis. Emricasan has been granted fast track designation by the FDA for the treatment of non-alcoholic steatohepatitis cirrhosis.
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