ER-000444793

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Purity: 95%

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N-(2-benzylphenyl)-2-oxo-1H-quinoline-4-carboxamide ER-000444793

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Application:For research use only.
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ER-000444793, a potent inhibitor of mitochondrial permeability transition pore (mPTP) opening, inhibits mPTP with an IC50 of 2.8?μM. R-000444793 neither affected cyclophilin D (CypD) enzymatic activity, nor displaced of CsA from CypD protein, suggesting a mechanism independent of CypD inhibition.

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