5-(ethylsulfonyl)-2-(naphthalen-2-yl)benzo[d]oxazole BMN-195
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Ezutromid, also known as BMN-195 and SMTC-1100, is an orally bioavailable and non-toxic small molecule that transcriptionally upregulates the utrophin gene (EC50= 0.4 uM), increasing both utrophin mRNA and protein. It significantly reduces dystrophin-deficient muscle pathology in vivo.
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