Fatostatin A

Fatostatin A

Fatostatin A

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Fatostatin 4-(4-Methylphenyl)-2-(2-Propyl-4-Pyridinyl)Thiazole

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Fatostatin (125B11) is an inhibitor of SREBP activation and prevents SCAP-mediated escort of SREBP-1 or SREBP-2 to the Golgi (IC50 = 5.6 μM). Fatostatin has anti-tumor properties and can reduce hyperglycemia in ob/ob mice.

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