[1,1'-Biphenyl]-4-carboxamide, N-[4-methoxy-3-(4-methyl-1-piperazinyl)phenyl]-2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)- N-[4-Methoxy-3-(4-methyl-1-piperazinyl)phenyl]-2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)[1,1'-biphenyl]-4-carboxamide
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GR 127935 is a potent and selective 5-HT1B/1D receptor antagonist (pKi = 8.5 for both guinea pig 5-HT1D and rat 5-HT1B receptors), exhibiting >100-fold selectivity over 5HT1A, 5-HT2A, 5-HT2C receptors and other receptor types.
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