GSK25 GSK 25
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GSK-25 is a potent, selective and orally bioavailable ROCK1 inhibitor with an IC50 of 7 nM. GSK-25 maintains good selectivity against a panel of 31 kinases (>100 fold), as well as RSK1 and p70S6K (RSK1: IC50 = 398 nM, p70S6K: IC50 = 1 μM).
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