HA-1004 monohydrochloride

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Purity: 95%

Keywords

5-Isoquinolinesulfonamide, N-[2-[(aminoiminomethyl)amino]ethyl]-, hydrochloride (1:1) 5-Isoquinolinesulfonamide, N-[2-[(aminoiminomethyl)amino]ethyl]-, monohydrochloride

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Appearance:White to Off-white Solid
Application:A novel calcium antagonist and vasodilator with no effect on cardiac function.
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Storage:Store at -20°C
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HA-1004 is a potent inhibitor of PKA and PKG with Ki values of 2.3 and 1.4 μM, respectively. It also inhibits PKC and calcium channel protein. HA-1004 was studied as a relaxant for rabbit aortic strips contracted by various agonists, suggesting its potential use for vasorelaxation.

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