Histone Acetyltransferase Inhibitor II (2E,6E)-2,6-bis[(3-bromo-4-hydroxyphenyl)methylidene]cyclohexan-1-one
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HAT Inhibitor II is a cell-permeable and selective inhibitor of the histone acetyltransferase p300 (IC50 = 5 μM). It has been shown to decrease histone H3 acetylation (IC50 ≤ 40 μM) and induce chromatin condensation in HeLa cells.
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