NSC301209 1-[2-(2,4-dichlorophenyl)-4-(4-fluorophenoxy)butyl]imidazole
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IMB-301 is a specific HIV-1 replication inhibitor that binds to hA3G (human APOBEC3G, a restriction factor that inhibits human immunodeficiency 1 virus (HIV-1) replication), blocks hA3G-Vif interaction and inhibits Vif-mediated hA3G degradation. It inhibits HIV-1 replication in H9 cells with an IC50 of 8.63 uM.
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