Indirubin-5-sulfonate

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Purity: ≥95%

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Indirubin-5-sulphonate 2-Oxo-3-(3-oxo-1,3-dihydro-2H-indol-2-ylidene)-5-indolinesulfonic acid

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Indirubin-5-sulfonate is an inhibitor of cyclin-dependent kinase (CDK), with IC50s of 55 nM, 35 nM, 150 nM, 300 nM and 65 nM for CDK1/cyclin B, CDK2/cyclin A, CDK2/cyclin E, CDK4/cyclin D1 and CDK5/p35, respectively. It also has an inhibitory effect on GSK-3β.

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