Ipatasertib HCl

Ipatasertib HCl

Ipatasertib HCl

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  • Min.Order :0
  • Purity: 95%

Keywords

(S)-2-(4-chlorophenyl)-1-(4-((5R,7R)-7-hydroxy-5-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)piperazin-1-yl)-3-(isopropylamino)propan-1-one hydrochloride. GDC0068

Quick Details

  • Appearance:Solid powder
  • Application:For research use only.
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  • Storage:Store in a cool and dry place (or refer to the Certificate of Analysis).
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Details:

Ipatasertib, also known as GDC-0068, is a highly selective pan-Akt inhibitor targeting Akt1/2/3 (IC50= 5 nM/18 nM/8 nM in cell-free assays) with 620-fold selectivity over PKA. Ipatasertib is advancing in clinical development including a Phase 3 trial in patients with prostate cancer and three Phase 2 trials in patients with breast cancer, gastric cancer and prostate cancer.

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