7,8,13,13a-tetradehydro-3-hydroxy-2,9,10-trimethoxy-Berbinium, hydroxide Neprotine hydroxide
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Jatrorrhizine Hydroxide is hydroxide salt of Jaztorrhizine, which is an alkaloid extracted from the Berberidaceae family of plants displaying antioxidant activity. Jatrorrhizine hydroxide is a potent and orally active inhibitor of AChE (IC50=872 nM) over >115-fold selectivity for BuChE. Jatrorrhizine hydroxide reduces uptake of serotonin (5-HT) and norepinephrine (NE) via inhibition of uptake-2 transporters.
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