JH-II-127

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Purity: 95%

Keywords

[4-[[5-chloro-4-(methylamino)-7H-pyrrolo[2,3-d]pyrimidin-2-yl]amino]-3-methoxyphenyl]-morpholin-4-ylmethanone<br/>JH-II-127<br/>(4-((5-chloro-4-(methylamino)-7H-pyrrolo[2,3-d]pyrimidin-2-yl)amino)...

Quick Details

Appearance:Light yellow to yellow Solid
Application:For research use only.
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Storage:Store in a cool and dry place and at 0 - 4°C for short term (days to weeks) or -74°C for long term (months to years).
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Details:

JH-II-127, a Pyrrolopyrimidine derivative, is a highly potent, selective, and brain penetrant LRRK2 inhibitor, of both wild-type and G2019S mutant LRRK2.
IC50: LRRK2-wild-type= 6.6 nM, LRRK2-G2019S= 2.2 nM ,LRRK2-A2016T= 47.7 nM

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