JLK 6

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Min.Order :0
Purity: 95%

Keywords

JCP-251 JCP 251

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Appearance:Yellow solid
Application:For research use only.
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Storage:Store in a cool and dry place and at 0 - 4°C for short term (days to weeks) or -26°C for long term (months to years).
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JLK 6, under the IUPAC name 7-amino-4-chloro-3-methoxyisochromen-1-one, an inhibitor of γ-secretase (IC50 = between 10 μM-1 mM) that belongs to the class of isocoumarin analogs, prevents recovery of Aβ40 and Aβ42 (IC50 < 100 μM) in HEK293 cells overexpressing wild-type and Swedish-mutant β-amyloid precursor protein (APP).

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