JNJ-38158471

JNJ-38158471

JNJ-38158471

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  • Purity: 95%

Keywords

CS-2660 (E)-1-(4-((6-amino-5-((methoxyimino)methyl)pyrimidin-4-yl)oxy)-2-chlorophenyl)-3-ethylurea

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JNJ-38158471 is a well tolerated, orally available and highly selective VEGFR-2 inhibitor with IC50 of 40 nM. JNJ-38158471 also inhibits closely related tyrosine kinases, Ret (180 nM) and Kit (500 nM).

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