Kobophenol A

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Purity: ≥95%

Keywords

(2S,2'R,3S,3'R)-3'-(3,5-Dihydroxyphenyl)-4-[(2S,3S,4R,5S)-4-(3,5-dihydroxyphenyl)tetrahydro-2,5-bis(4-hydroxyphenyl)-3-furanyl]-2,2',3,3'-tetrahydro-2,2'-bis(4-hydroxyphenyl)[3,4'-bibenzofuran]-6,...

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Appearance:Powder
Application:For research use only.
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Storage:Store at 2-8°C, sealed storage, away from moisture and light
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Kobophenol A is a natural product found in Caragana korshinskii and Carex folliculata. Kobophenol A blocks the interaction between the ACE2 receptor and S1-RBD with an IC50 of 1.81 μM and inhibits SARS-CoV-2 viral infection in cells with an EC50 of 71.6 μM. It inhibits the activity of partially purified rat brain protein kinase C (PKC) with an IC50 of 52 μM.

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