L-745870 hydrochloride

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Purity: ≥95%

Keywords

1H-Pyrrolo(2,3-b)pyridine, 3-((4-(4-chlorophenyl)-1-piperazinyl)methyl)-, hydrochloride (1:1) 1-(4-chlorophenyl)-4-({1H-pyrrolo[2,3-b]pyridin-3-yl}methyl)piperazine hydrochloride

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Appearance:White Solid
Application:For research use only.
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Storage:Store at 2-8°C, sealed storage, away from moisture
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L-745870 hydrochloride is a potent, selective, brain-penetrant and orally active antagonist of dopamine D4 receptor (Ki = 0.43 nM). It exhibits weaker affinity for D2 (Ki = 960 nM) and D3 (Ki = 2300 nM) receptors, and moderate affinity for 5-HT2 receptors, sigma sites and α-adrenergic receptor.

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