LLY-507 LLY 507
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LLY-507, a lysine N-methyltransferase, is a cell-active, small molecule, and selective inhibitor of Protein-lysine Methyltransferase SMYD2 (IC50 = 15 nM), with >100-fold selectivity for SMYD2 over 25 other methyltransferases including SMYD3, SUV420H1 and SUV420H2.
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