[(5-phenyl-1,3,4-oxadiazol-2-yl)carbamoyl]methyl 2-{naphtho[2,1-b]furan-1-yl}acetate Naphtho[2,1-b]furan-1-acetic acid, 2-oxo-2-[(5-phenyl-1,3,4-oxadiazol-2-yl)amino]ethyl ester
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LtaS-IN-1 is a potent small-molecule inhibitor that inhibits multidrug-resistant (MDR) E. faecium Lipoteichoic acid (LTA) synthesis by altering cell wall morphology. LtaS-IN-1 alone inhibits Enterococcus.spp 28 strains with varying MIC values ranging from 0.5 μg/mL to 64 μg/mL. LtaS-IN-1 combined antibiotics almost completely abolish the growth of multidrug-resistant E. faecium.
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