3-[(3E,7E)-4,8-dimethyl-10-(2,6,6-trimethylcyclohexen-1-yl)deca-3,7-dienyl]-2-hydroxy-2H-furan-5-one
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Luffariellolide is a natural sesterterpenoid isolated from the Palauan spongeLuffariella sp. It reversibly inhibits phospholipase A2, displaying anti-inflammatory activity. It also acts as an agonist for the RA receptors RAR α, β, and γ but not for other nuclear receptors.
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