5-[[4-[[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]-1H-indole-2-carbonitrileMI-136 MI 136
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MI-136, with the potential to treat refractory prostate cancer, inhibits DHT-induced expression of androgen receptor (AR) target genes.
In vitro: Treatment with MI-136 inhibits the expression of genes that are bound to ASH2L after AR stimulation and induc
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