MK-386

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Purity: ≥98% by HPLC

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MK 386 MK386

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Application:5-alpha Reductase Inhibitors
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MK-386 is a human type I 5α-reductase inhibitor with selectivity for type I 5α-reductase over type II 5α-reductase (IC50 = 0.9 and 154 nM, respectively). It reduces dihydrotestosterone (DHT) in serum and sebum in a dose-dependent manner, suggesting its utilization in acne treatment.

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