(E)-3-(3-chlorophenyl)-N-[2-[(1,1-dioxothian-4-yl)-methylamino]-2-oxoethyl]prop-2-enamideML264 ML264
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ML264 is a Krüppel-like factor 5 (KLF5) inhibitor with the potential to inhibits growth of colorectal cancer. It reduces EGR1 and KLF5 levels so that ML264 inhibits the MAPK pathway.
in a cell-based assay for proliferation of DLD-1 cells: IC50 = 29 nM, in
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