- Min.Order :0
- Purity: ≥98%
Keywords
MS-37452 MS 37452
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- Appearance:Crystalline Solid
- Application:For research use only.
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MS37452 is a competitive inhibitor of CBX7 chromodomain (CBX7ChD) binding to H3K27me3 (Ki = 43 μM). It inhibits CBX7ChD binding to H3K27me3 at the INK4A/ARF locus, inducing transcriptional de-repression of p16/CDKN2A in PC3 prostate cancer cells.
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