MSOP

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Purity: 95%

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(RS)-α-Methylserine-O-phosphate Alpha-MSOP

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MSOP is a selective group III metabotropic glutamate receptor (mGluR) antagonist. MSOP exhibits an apparent KD of 51 μM for the L-AP4-sensitive presynaptic mGluR on primary afferent terminals in spinal cord compared to > 700 μM for the (1S,3S)-ACPD-sensitive presynaptic mGlu in the same system. MSOP has no effect on postsynaptic mGlu receptors or on ionotropic glutamate receptors on neonatal rat motoneurons.

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