NH-3

NH-3

NH-3

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  • Purity: ≥95%

Keywords

Thyromimetic, 5b Acetic acid, 2-(4-((4-hydroxy-3-(1-methylethyl)-5-(2-(4-nitrophenyl)ethynyl)phenyl)methyl)-3,5-dimethylphenoxy)-

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NH-3, a derivative of selective thyromi-metic GC-1, is an orally active and reversible thyroid hormone receptor (THR) antagonist with an IC50 of 55 nM. It inhibits the binding of thyroid hormones to their receptors and inhibits cofactor recruitment.

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