NZ 419 5-Hydroxy-1-methylhydantoin
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NZ-419 is an antioxidant potentially for the treatment of renal failure. NZ-419 completely suppressed the expression of B2-kinin receptors (B2KR) in response to high glucose (25 mM) stimulation in VSMC and was also shown to attenuate the effects of BK on VSMC remodeling.
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