OBI-3424

OBI-3424

OBI-3424

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  • Purity: ≥95%

Keywords

TH-3424 Phosphinic acid, P,P-bis(1-aziridinyl)-, (1R)-1-(3-(3-((dimethylamino)carbonyl)phenoxy)-4-nitrophenyl)ethyl ester

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  • Appearance:Solid Powder
  • Application:For research use only.
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  • Storage:Store at -20°C, protect from light
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Details:

OBI-3424 is a highly selective prodrug that is converted by AKR1C3 (aldo-keto reductase 1C3) to a potent DNA-alkylating agent. It can be used in studies of hepatocellular carcinoma, castrate-resistant prostate cancer, and acute lymphoblastic leukemia (ALL).

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