OP-1074

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Purity: ≥95%

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(2S)-3-(4-hydroxyphenyl)-4-methyl-2-(4-{2-[(3R)-3-methylpyrrolidin-1-yl]ethoxy}phenyl)-2H-1-benzopyran-7-ol 2H-1-Benzopyran-7-ol, 3-(4-hydroxyphenyl)-4-methyl-2-[4-[2-[(3R)-3-methyl-1-pyrrolidinyl]ethoxy]phenyl]-, (2S)-

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Application:Estrogen Receptor Antagonists
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Storage:Store at -20°C, stored under nitrogen, away from moisture
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OP-1074, a pure antiestrogenic agent, is a selective ER degrader (PA-SERD) that has specific antiestrogenic activity against ERα and ERβ, inhibiting transcription activity stimulated by 17β-estradiol (E2) with IC50s of 1.6 and 3.2nM, respectively.

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