SP-8203 Acetamide, N-[3-(1,4-dihydro-2,4-dioxo-3(2H)-quinazolinyl)propyl]-N-[4-[[3-(1,4-dihydro-2,4-dioxo-3(2H)-quinazolinyl)propyl]amino]butyl]-
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Otaplimastat, a reactive oxygen species inhibitor and superoxide dismutase stimulant, has been used in trials to investigate the treatment of ischemic stroke. It is a matrix metalloproteinase (MMP) inhibitor that competively blocks N-methyl-D-aspartate (NMDA) receptor-mediated excitotoxicity. It also has antioxidant activity.
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