Palmitoyl 3-carbacyclic phosphatidic acid

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Purity: ≥95%

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3-ccPA 16:0

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Appearance:Crystalline Solid
Application:For research use only.
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Palmitoyl 3-carbacyclic phosphatidic acid is a cyclic LPA analog containing the 16:0 fatty acid, palmitate, at the sn-1 position of the glycerol backbone. At 25 μM, it inhibits the transcellular migration of MM1 cells across mesothelial cell monolayers in response to fetal bovine serum (81.9%) or LPA (98.9%) without affecting proliferation. It has been shown to inhibit autotaxin (IC50 = 620 nM).

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