PAWI-2

PAWI-2

PAWI-2

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  • Purity: 99%

Keywords

Wnt-p53 inhibitor compound 2 1-(4-(4-Methyl-3,4-dihydroquinoxalin-1(2H)-ylsulfonyl)phenyl)pyrrolidin-2-one

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PAWI-2 is an inhibitor which targets both Wnt signaling (IC50 = 11 nM) and ATM/p53 (EC50 = 1.9 nM for p53). PAWI-2 is a new approach to reverse tumor stemness that resensitizes CSC tumors to drug inhibition.

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