PF-02413873 4-((3-cyclopropyl-5-methyl-1-((methylsulfonyl)methyl)-1H-pyrazol-4-yl)oxy)-2,6-dimethylbenzonitrile
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PF-2413873 is a potent selective, and orally active nonsteroidal progesterone receptor (PR) antagonist, with a Ki of 2.6 nM. PF-2413873 can block progesterone binding and PR nuclear translocation, and inhibit endometrial growth in vivo.
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