Pyridoxal-5'-phosphate-6-(2'-naphthylazo-6'-nitro-4',8'-disulfonate) tetrasodium salt
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PPNDS is a potent and selective P2X1 receptor antagonist (pKB = 7.43 in rat vas deferens). PNDS is approximately 50-fold less selective for P2Y1R and does not interact with α1A-adrenergic, adenosine A1 and A2B, histamine H1, or muscarinic M3 receptors.
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