Protein Tyrosine Phosphatase Inhibitor IV Bis(4-Trifluoromethylsulfonamidophenyl)-1,4-diisopropylbenzene
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PTP inhibitor IV is an uncharged, 1,4-di-substituted, phenyl-linked bis-trifluoromethylsulfonamido phosphate mimetic that acts as a reversible, competitive, and active-site directed inhibitor of SHP-2, PTP1B, PTP-ε, PTP-Meg-2, PTP-σ, PTP-β, and PTP-μ (IC50s = 1.8, 2.5, 8.4, 13, 20, 6.4, and 6.7 μM, respectively).
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