N-[4-[3,5-bis(trifluoromethyl)pyrazol-1-yl]phenyl]-3-fluoropyridine-4-carboxamidePyr6 Pyr-6
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Pyr6, a pyrazole derivative, is a selective inhibitor of ransient receptor potential cation 3 (TRPC3) channels that inhibited Orai1- and TRPC3-mediated Ca(2+) entry. IC50= 0.49 uM(Ca2+ influx inhibition in thapsigargin depleted native RBL-2H3 cells)
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