1-(3,4-dichlorophenyl)-3-(4-methoxyphenyl)-4-morpholin-4-ylpyrrole-2,5-dioneRI-2 RI 2
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RI-2, a fully reversible RAD51 inhibitor (IC50 = 44.2 μM) that had been treated with RI-2 prior to washing exhibited no measurable loss of DNA binding activity.
In vitro: It has been shown to inhibit DNA repair and to sensitize cancer cells to cross-linki
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