18-Hydroxyseneciphylline (15Z)-12,18-Dihydroxy-13,19-didehydrosenecionan-11,16-dione
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Riddelline, a pyrrolizidine alkaloid, is a potent genotoxic substance. In vivo, riddelline induces micronucleus in mouse bone marrow and peripheral blood, as well as S-phase synthesis and unscheduled DNA synthesis in rat and mouse liver.
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