RO8191

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Purity: ≥98%

Keywords

Ro 494-8191 2-[2,4-bis(trifluoromethyl)imidazo[1,2-a]1,8-naphthyridin-8-yl]-1,3,4-oxadiazole

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Appearance:Crystalline Solid
Application:For research use only.
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Storage:-20°C, stored under nitrogen<br/>* In solvent :<br/>-80°C 6 months<br/>-20°C 1 month (stored under nitrogen)
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RO8191 is an agonist of interferon α receptor type 2 (IFNAR2) effective against HCV with EC50 value of 200 nM. RO8191 phosphorylates STAT1 and STAT2, which functions as a gateway to the type I IFN signal cascade, and stimulates the phosphorylation of STAT3, 5 and 6.

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