Rottlerin

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Purity: ≥98% (HPLC)

Keywords

3'-[(8-Cinnamoyl-5,7-dihydroxy-2,2-dimethyl-2H-1-benzopyran-6-yl)methyl]-2',4',6'-trihydroxy-5'-methylacetophenone

Quick Details

Appearance:Brown to reddish brown (Solid)
Application:Enzyme Inhibitors
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Storage:Store in a cool and dry place (or refer to the Certificate of Analysis).
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We provide customized and high-quality Rottlerin product for your project.

Details:

Rottlerin, a principal phenolic compound of the Kamala plant Mallotus philippinensis, originally reported to inhibit PKC isoforms, especially PKCδ and CAM-KIII. Recently, it has been shown to inhibit a wide range of protein kinases, and most potently to inhibit PRAK and MAPKAP-K2 (IC50 values are 1.9 and 5 μM respectively).

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