Oxprenoate potassium (7α,17α)-17-Hydroxy-3-oxo-7-propylpregn-4-ene-21-carboxylic acid potassium salt
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RU 28318 is a potent and selective antagonist of mineralocorticoid receptor (MR). It inhibits aldosterone production and secretion, and selectively decreases ex-vivo MR binding in the hippocampus of adrenalectomised rats. It also decreases blood pressure in female rats following central administration in vivo.
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