(E)-(5)-(3,5-di-tert-butyl-4-hydroxybenzylidene)-2-ethyl-1,2-isothiazolidine-1,1-dioxide Phenol, 2,6-bis(1,1-dimethylethyl)-4-[(E)-(2-ethyl-1,1-dioxido-5-isothiazolidinylidene)methyl]-
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S-2474 is a COX-2 and 5-lipoxygenase (5-LO) inhibitor, with IC50s of 11 nM and 27 μM for COX-2 and COX-1 in human intact cells, respectively. S-2474 is used as a nonsteroidal anti-inflammatory drug.
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