7H-Indolo[1,7-bc][2,6]naphthyridine, 4,5,7a,8,9,10,11,11a-octahydro-10-methyl-, (7aR,11aS)-rel- 7H-Indolo[1,7-bc][2,6]naphthyridine, 4,5,7a,8,9,10,11,11a-octahydro-10-methyl-, cis-
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SDZ SER 082 is a selective 5-HT2B/2C receptor antagonist with low affinity for 5-HT1A receptors. SDZ SER 082 inhibits [3H]-mesulergine binding to 5-HT2C receptors (pKD = 7.8), and suppresses 5-HT2B mediated responses in the rat fundus (pKB = 7.34).
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