SKF 83959

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Purity: ≥95%

Keywords

1H-3-Benzazepine-7,8-diol, 6-chloro-2,3,4,5-tetrahydro-3-methyl-1-(3-methylphenyl)- 6-Chloro-2,3,4,5-tetrahydro-3-methyl-1-(3-methylphenyl)-1H-3-benzazepine-7,8-diol

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Appearance:White Solid
Application:For research use only.
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SKF 83959 is a dopamine D1-like receptor partial agonist (Ki = 1.18, 7.56, 920 and 399 nM for rat D1, D5, D2 and D3 receptors, respectively), exhibiting anti-Parkinsonian effects and antagonizing the behavioral effects of cocaine. SKF 83959 also acts as an allosteric modulator of the σ1 receptor via potentiating binding of the σ1 receptor.

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