VXc-486 (R)-1-ethyl-3-(6-fluoro-5-(2-(2-hydroxypropan-2-yl)pyrimidin-5-yl)-7-(tetrahydrofuran-2-yl)-1H-benzo[d]imidazol-2-yl)urea
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SPR719 is a gyrase B inhibitor with bactericidal activity. It has strong inhibitory effect on multiple drug-sensitive isolates and drug-resistant isolates of Mycobacterium tuberculosis, with MICs of 0.03-0.30 μg/ml and 0.08-5.48 μg/ml, respectively.
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