CasNo.187034-31-7,TAPI-2,N-(R)-[2-(Hydroxyaminocarbonyl)methyl]-4-methylpentanoyl-L-t-butyl-alanyl-L-alanine, 2-aminoethyl Amide(187034-31-7) Suppliers

0	Negotiable

Min.Order :0
Purity: ≥95%

Keywords

TNF Protease Inhibitor 2 N-[(2S)-1-[[(2S)-1-(2-Aminoethylamino)-1-oxopropan-2-yl]amino]-3,3-dimethyl-1-oxobutan-2-yl]-N'-hydroxy-2-(2-methylpropyl)butanediamide

Quick Details

Appearance:Crystalline Solid
Application:For research use only.
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Storage:4°C, sealed storage, away from moisture and light<br/>* In solvent :<br/>-80°C 6 months;<br/>-20°C 1 month (sealed storage, away from moisture and light)
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TAPI-2 is a broad-spectrum inhibitor of TNF-α converting enzyme (TACE; ADAM17), other ADAMs and matrix metalloproteinases (MMPs). It inhibits phorbol-12-myristate-13-acetate-induced (PMA) shedding of various cell surface proteins, such as TGF-α, β amyloid precursor protein, L-selectin, and IL-6 receptor α subunit.