THZ2

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Purity: 95%

Keywords

N-[3-[[5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl]amino]phenyl]-3-[[(E)-4-(dimethylamino)but-2-enoyl]amino]benzamideTHZ2 THZ 2

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Appearance:Solid powder
Application:For research use only.
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Storage:Store in a cool and dry place and at 0 - 4°C for short term (days to weeks) or -22°C for long term (months to years).
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THZ2, an analog of THZ1, with the potential to treat Triple-negative breast cancer (TNBC), it is a potent and selective CDK7 inhibitor which overcomes the instability of THZ1 in vivo.
IC50: CDK7= 13.9 nM; TNBC cells= 10 nM

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