TMP-153

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Purity: ≥95%

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N-(4-(2-Chlorophenyl)-6,7-dimethyl-3-quinolyl)-N'-(2,4-difluorophenyl)urea 1-[4-(2-chlorophenyl)-6,7-dimethylquinolin-3-yl]-3-(2,4-difluorophenyl)urea

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Appearance:Crystalline Solid
Application:For research use only.
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TMP-153 is an Acyl-CoA:cholesterol acyltransferase (ACAT) inhibitor with IC50 values of 5-10 nM in various animals. It inhibits cholesterol esterification both in human colonic adenocarcinoma cells, LS180, and in human hepatoma cells, HepG2 (IC50 = 150 nM and 330 nM, respectively).

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